Atchison County Historical Museum is dedicated to collecting, preserving, and displaying objects related to Atchison County history. It is housed in the restored Santa Fe Depot building in Atchison, Missouri.
Through its impressive collection of guns, railroad memorabilia and Amelia Earhart's personal effects, the museum throws light on the rich historic past of Atchison county, and the state of Missouri as a whole.
It also has several exhibits related to the Lewis and Clark Expedition and showcases one of three resin models produced of the full-scale Lewis and Clark statue in Case Park in downtown Kansas City, Missouri.
Members of the historical society are provided access to research resources.